COMPARATIVE STUDY ON THE EFFECT OF RADIATION ON WHOLE BLOOD AND ISOLATED RED BLOOD CELLS

NABILA S. SELIM

Molecular Biophysics Laboratory, Radiation Physics Department, National Center for Radiation Research and Technology (NCRRT), AEA, POB 29, Madinat Nasr, Cairo, Egypt

Abstract. Assessment of the dielectric properties of red blood cells requires several steps for preparation and isolation from whole blood. These steps may result in changes in the cells properties, and they are time consuming. The present study aims to compare the properties of both whole blood and isolated red blood cells and the effect of gamma radiation on these properties. Adult male rats were exposed to 1, 3.5 and 7 Gy as single dose, from Cs-137 source. The studies dielectric properties, in the frequency range 40 kHz to 5 MHz, and light scattering studies for suspensions of whole blood and isolated red blood cells from the same groups were measured. The obtained results showed that whole blood and red blood cells suspensions followed the same trend in their response to radiation, which suggests the possibility of using whole blood suspension for the evaluation of the red blood cells properties.
Key words: Blood, red blood cells, gamma radiation, dielectric properties

Author’s e-mail: selimnabila@yahoo.com

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