SIMONA CAVALU, VIORICA SIMON, F. BĂNICĂ, C. DELEANU

Faculty of Medicine and Pharmacy, University of Oradea, 10, P-ţa 1 Decembrie, Oradea, Romania

Sol-gel method was chosen in order to prepare different aluminosilicate materials. This study is focused on FTIR spectroscopy and differential thermal analysis of Al2O3-SiO2 binary system, followed by Simulated Body Fluid investigation as bioactivity evidence. The biocompatibility of the samples was evaluated with respect to fibrinogen adsorption using ATR FTIR technique. Deconvolution of amide I band of fibrinogen upon adsorption indicates that aluminosilicates prepared with silicic acid as starting material exhibit a superior biocompatibility compared with that of the sample obtained with TEOS.

Corresponding author’s e-mail: scavalu@rdslink.ro

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