FTIR STUDIES ON THE CONCOMITANT EFFECTS OF SILDENAFIL CITRATE AND ETHANOL ON KIDNEY OF ALBINO MICE

K. SOUMYA*, R. UDAYAKUMAR**, K. VISWANATHAN*#

*Department of Physics, Karpagam University, Coimbatore – 21, India
**Department of Physics, Faculty of Science, Annamalai University, Annamalai Nagar – 608 002, Tamil Nadu, India

Abstract. Male Wistar albino mice were co-administered with appropriate dose of sildenafil citrate and ethanol. The kidney samples of those animals were analysed for their lipid content using FTIR spectral technique. Specific extinction coefficient (K) values for various functional groups of lipids present in kidney samples of each group were determined. From the present investigation an enhanced level of lipid peroxidation was detected for 30 days animals treated concomitantly with sildenafil citrate and ethanol.
Key words: Albino mice, kidney, sildenafil citrate, ethanol, lipids, FTIR spectroscopy

Author’s e-mail: Soumya.preethu@gmail.com

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