HEPZI PRAMILA JUSTIN*, NANCY BEAULAH RATHINAM**, KARUNAI SELVI BALAN***#, VIJAYA VELU****, LALITHAMBIGAI SHENBAGARAJAN*, SUSMITHA NARAYANASAMY*
https://www.doi.org/10.59277/RJB.2025.2.02
*Department of Physics, ”V.V.Vanniaperumal” College for Women, Virudhunagar – 626 001, Tamil Nadu, India
**Department of Computer Applications, ”V.V.Vanniaperumal” College for Women, Virudhunagar – 626 001, Tamil Nadu, India
***Department of Botany, ”V.V.Vanniaperumal” College for Women, Virudhunagar – 626 001, Tamil Nadu, India
****Department of Botany, ”E.M.G. Yadava” Women’s College, Madurai – 625014, Tamil Nadu, India
Ag-doped zinc hydroxide nanoparticles were synthesized using the leaf extract of Tridax procumbens through a chemical co-precipitation method. The synthesized sample was characterized using powder X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDAX), ultraviolet spectroscopy (UV), and Fourier transform infrared spectroscopy (FTIR). XRD analysis confirmed the preferential growth of Ag-doped zinc hydroxide nanoparticles with an average width of 42 nm. SEM imaging revealed that the nanoparticles exhibited a spherical morphology. EDAX spectra confirmed the elemental composition of the sample, while FTIR spectroscopy was used to analyze the stretching and bending frequencies of molecular functional groups. The UV spectrum determined the band gap energy of the nanoparticles to be 4.5 eV. Antibacterial studies demonstrated that the antimicrobial activity of the synthesized nanoparticles increased proportionally with concentration. Additionally, MTT assay results indicated significant cytotoxic activity against MDA-MB-231 cells, with Ag-doped nanoparticles exhibiting maximum effects on cell viability at a low concentration of 20 µg/mL, surpassing the effects observed with Tridax procumbens extract alone.
Key words: Ag-doped, Tridax procumbens, nanoparticle, structural characterization, biomedical applications
Corresponding author’s e-mail:karunaiselvi@vvvcollege.org, karunaiselvi@gmail.com