ALEXANDRA FĂLĂMAŞ*,***, SIMONA CÎNTĂ-PÎNZARU*, C. DEHELEAN**, CH. KRAFFT***, J. POPP***,****
*Faculty of Physics,”Babeş-Bolyai” University, 1, Kogălniceanu st, 400084 Cluj-Napoca, Romania
** Faculty of Pharmaceutics, “Victor Babeş” University of Medicine and Pharmaceutics, 2, Eftimie Murgu Square, 300041 Timişoara, Romania
***Institute of Photonic Technology, Albert Einstein Straße 9, 07745 Jena, Germany
****Institute of Physical Chemistry, Helmholtzweg 4, 07743 Jena, Germany
Abstract. This paper presents a debut study of damaged tissues by 7, 12 dimethylbenzanthracene (DMBA) and UVB radiation. Before data acquisition samples were inoculated in formalin solution mixed with colloidal silver. The objective was to apply Raman, FT-IR and SERS spectroscopy to detect the structure and conformation of molecular components from tissues originating from wounded mouse models. These vibrational micro-spectroscopies can provide molecular information of the examined samples with a high spatial resolution at microscopic level. Raman imaging was applied to investigate areas from the tissues and identified SERS effect due to the added colloidal nanoparticles. The analysis of these spectra indicated chemisorption of the nanoparticles in the tissue.
Key words: UV radiation, SERS, mouse model, silver nanoparticles.
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