VITAMIN E REDUCES THE EFFECT OF MAGNETIC FIELD ON DEPRESSION IN THE BLOOD PARAMETERS AND IN THE INTEGRITY OF ERYTROCYTES IN ALBINO MICE

MAGDA HANAFY*#, S.A. NASSAR**, AMANY ELATTAR*, MANAR MOSTAFA***

*Physics department, Faculty of Science, Zagazig University, Egypt

**Zoology Department, Faculty of Science, Zagazig University, Egypt

         ***Legal  Medicine Department, Faculty of Medicine, Zagazig University, Egypt

In this work the effect of sinusoidal 50 Hz, 2 mT magnetic field generated by electrical devices was evaluated on the blood parameters, erythrocyte counts (red blood cells/ RBCs), hemoglobin content (Hb), toxicity, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), white blood cells (WBCs), platelet counts (PLT), osmotic fragility test, and blood film test. Three groups, each of 10 mice were used, group one used as unexposed (control), group two exposed to the field  for total  period (45 day, 2 hours/day) and group three exposed to the same field and period after adding vitamin E (20 mg/kg) body weight (b.wt.) in the drinking water. The result showed a significant depression in the blood parameters of group two relative to control group, but for group three blood parameters are improved. In addition, the hemolytic percentages were (0.40 %, 0.30 %, 0.35 %) for the control (group one), exposed (group two), protected (group three), respectively. Blood film showed low stainable leucocytes and crenate damaged erythrocytes for group two but for group three erythrocytes nearly restored their integrity. The results recorded showed that the side effects of magnetic field on the blood of mice decreased after using antioxidant vitamin E.  

Key words: Electromagnetic field, blood parameters, osmotic fragility, blood film, vitamin E

Corresponding author’s e-mail: mshanafy@zu.edu.eg

 

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