ANTIFUNGAL ACTIVITY OF ZINC OXIDE NANOPARTICLES AGAINST DERMATOPHYTIC LESIONS OF CATTLE

EMAN M. EL-DIASTY*, M.A AHMED***, NAGWA OKASHA****, SALWA .F. MANSOUR*****, SAMAA I.EL-DEK***, HANAA M. ABD EL-KHALEK**, MARIAM H. YOUSSIF**

*Mycology Department, Animal Health Research Institute, Dokki, Egypt
**Buffalo disease Department, Animal Health Research Institute, Dokki, Egypt
***Materials Science Lab (1), Physics Department, Faculty of Science, Cairo University, Giza, Egypt
**** Physics Department, Girls College, Ain Shams University, Cairo, Egypt
***** Physics Department, Faculty of Science, Zagazig University, Zagazig, Egypt

Ringworm is a fungal and zoonotic infectious disease, caused by different species of dermatophytes. In this study, skin scrapings and hair samples were collected from 50 cattle with clinical symptoms of dermatophytosis. The collected samples were directly examined for fungal elements by direct microscopy. Isolates of Dermatophytes were found to be 14.3% and 26.6% for samples obtained from cow and buffaloes respectively. The distribution of isolates was Trichophyton mentagrophyte (33.33%), Micsporum canis (26.67%), Candida albicans (26.67%), Aspergillus fumigatus (13.33%) respectively. The antifungal activity of zinc oxide (ZnO) nanoparticles was evaluated for Trichophyton mentagrophyte, Microsporum canis, Candida albicans and Aspergillus fumigatus. The largest inhibition in the germination of all the tested fungi was observed at largest ZnO nanoparticles concentration (40 mg/mL).

Corresponding author’s e-mail: moala47@hotmail.com

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