LUISA ANDRONIE*, SIMONA CÎNTĂ PÂNZARU**, O. COZAR*, I. DOMŞA***
*Biomedical Physics Department, ”Babeş-Bolyai” University, 1, M. Kogălniceanu st, Cluj-Napoca, Romania
**Molecular Spectroscopy Department, “Babeş-Bolyai” University, 1, M. Kogălniceanu st, Cluj-Napoca, Romania
***Department of Pathological Anatomy, CFR University Hospital Cluj-Napoca, 16–18, Republicii st, Cluj-Napoca, Romania
Abstract. The human colon carcinoma and normal tissues were investigated using FT-IR spectroscopy. The preliminary studies demonstrate that it is possible to probe individual chemical species and molecular signaling within the normal and colon carcinoma tissue, drawing first step toward cancer molecular profiling. The molecular structural changes induced by the disease in the studied samples were identified based on the relative intensity of the bands assigned to the lipid/protein content. The results obtained in this study are in good agreement with the recent reports.
Key words: FT-IR, colon tissue, adenocarcinoma.
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