SEHAM M. EL-MARAKBY#, NABILA S. SELIM
Biophysics Laboratory, Radiation Physics Department, National Center for Radiation Research and Technology (NCRRT), Atomic Energy Authority (AEA), POB 29, Madinat Nasr Cairo, Egypt
This work is intended to study the radio-mitigation effect of rutin on the dielectric properties of blood. Adult male rats were divided into four groups: control, positive control (treated with rutin for four consecutive weeks), irradiated and irradiated and treated groups. The latter group was treated with rutin for four consecutive weeks after irradiation. The exposure dose was 6 Gy gamma radiation. The electrical properties of blood were measured. The relative permittivity, relaxation time, and area under the loss curve showed significant decrease after exposure to gamma radiation (i.e., in the case of irradiated group) compared to control group. However, the positive control group and the treated group with rutin after irradiation showed a non-significant decrease as compared to the control group. The treatment with rutin resulted in a significant decrease in the effective capacitance (Ceff) of erythrocytes membrane compared to control group, while, it did not show significant changes in the irradiated and the treated groups after irradiation. On the other hand, the AC conductivity decreased after exposure to gamma radiation, while no significant changes were observed for the positive control and the treated groups with rutin after irradiation, compared to the control. The treatment with rutin after exposure to radiation was shown to mitigate the damaging effects in the erythrocytes’ membrane.
Key words: rutin, gamma radiation, blood, dielectric properties.
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