EVA KATONA*, GYONGYVER KATONA**, A. CĂPLĂNUȘI**, I. O. DOAGĂ*, DIANA IONESCU*, R. MATEI*, JUDIT HORVATH***, E. TRUȚIA**, E. TANOS***, L. KATONA
*Department of Biophysics, „Carol Davila” University of Medicine and Pharmaceutics, Bucharest, Romania
** Department of Medical Biochemistry, „Carol Davila” University of Medicine and Pharmaceutics, Bucharest, Romania
***Lasereuropa, OPTIKOP CO., Budapest, POB 405, Hungary
Abstract. The aim of the present work was to contribute to the understanding of the cellular and molecular mechanisms involved in low power long wavelength laser irradiation effects. Investigating the 680 nm laser light influence on the anisotropy of 1,6-diphenyl-1,3,5-hexatriene (DPH) and 1 [(4-trimethyl-amino)phenyl]-6-phenyl-1,3,5-hexatriene (TMA-DPH) fluorescence, we report low power red laser induced changes in the lipid order parameter in various regions of the plasma membrane of human platelets and peripheral blood lymphocytes. Using irradiation doses of therapeutic significance, dependence of the observed membrane effects on the actual metabolic state of cells is pointed out.
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