EVA KATONA*, GYONGYVER KATONA**, I.O. DOAGĂ*, TEOFILA SEREMET**, MARIA DUMITRESCU*, SÂNZIANA RADESI*, R. MATEI*, JUDIT HORVATH***, E. TANOS***, L. KATONA*
*Department of Biophysics, ** Department of Medical Biochemistry, „Carol Davila” University of Medicine and Pharmaceutics, Bucharest, Romania
***Lasereuropa, OPTIKOP CO., Budapest, POB 405, Hungary
Abstract. The aim of the present work was to contribute to the understanding of the cellular and molecular mechanisms involved in low power long wavelength laser irradiation effects. Investigating the 830 nm laser light influence on the anisotropy of 1 [(4-trimethyl-amino)phenyl]-6-phenyl-1,3,5-hexatriene (TMA-DPH) fluorescence, we report low power infrared laser induced changes in the lipid order parameter in the polar head group regions of human lymphocytes plasma membrane. Using irradiation doses of therapeutic significance, we point out a sensitive dependence of the observed membrane effects on the lymphocytes actual metabolic state.
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