RADIOPROTECTIVE EFFECT OF PALLADIUM α-LIPOIC ACID COMPLEX ON THE DIELECTRIC RELAXATION AND AC CONDUCTIVITY OF RED BLOOD CELLS

NABILA S. SELIM

Molecular Biophysics Laboratory, Radiation Physics Department, National Center for Radiation Research and Technology (NCRRT), POB.29, Cairo, Egypt

The present work studies the effect of palladium α-lipoic acid complex (PLAC) on the dielectric relaxation and AC conductivity of red blood cells and tests its effect as radioprotector. Blood sample were exposed to gamma radiation at dose level 100 Gy. The samples were divided into four groups: control, control with PLAC, irradiated and irradiated with PLAC. The dielectric properties were measured to determine the relative permittivity, dielectric loss and AC conductivity. The addition of PLAC to the blood samples resulted in increase in the relative permittivity, dielectric loss and AC conductivity of control red blood cells. While the exposure to gamma radiation affected their dielectric properties, the addition of PLAC to the RBCs prior to exposure to 100 Gy gamma radiation was shown to provide a significant protection from radiation-induced damage for the measured parameters in this study.

Author’s e-mail: selimnabila@yahoo.com

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